1 Introduction.- 2 Family History.- 3 The Role of Clinical Observation: Red Flag 1 - Cardiomyopathies and Skeletal Muscle Involvement.- 4 The Role of Clinical Observation: Red Flag 2 - Cardiomyopathies and Arrhythmias.- 5 The Role of Clinical Observation: Red Flag 3 - Cardiomyopathies, WPW Syndrome and Other ECG Abnormalities.- 6 The Role of Clinical Observation: Red Flag 4 - Cardiomyopathies and Sensorineural Hearing Loss.- 7 The Role of Clinical Observation: Red Flag 5 - Right Ventricular Involvement, Arrhythmogenic Right Ventricular Cardiomyopathy and Associated Phenotypes.- 8 The Role of Clinical Observation: Red Flag 6 - Left Ventricular Non-Compaction.- 9 The Role of Clinical Observation: Red Flag 7 - Syndromic and Multisystem Cardiomyopathies.- 10 The Role of Clinical Observation: Red Flag 8 - Cardiomyopathies in the First Year of Life and Paediatric Cardiomyopathies.- 11 Clinical Genetic Testing in Cardiomyopathies.- 12 Conclusive Remarks.