Part I: Introduction Hematopoiesis and Bone Marrow Histology Bone Marrow Examination and Techniques Bone Marrow Reporting Overview of Constitutional and Acquired Bone Marrow Disorders Part II: Anemia Overview of Anemia SECTION 1: ACQUIRED ANEMIAS Iron Deficiency Anemia Autoimmune Hemolytic Anemias Alloimmune Hemolytic Anemia and Hemolytic Disease of Newborn Microangiopathic Hemolytic Anemia Megaloblastic Anemia Acquired Nonneoplastic Sideroblastic Anemia Alcoholism-Associated Anemia Anemia in the Elderly Copper Deficiency-Associated Anemia Acquired Red Cell Aplasia Transient Erythroblastopenia of Childhood Parvovirus-Induced Red Cell Aplasia Paroxysmal Nocturnal Hemoglobinuria Acquired Aplastic Anemia SECTION 2: CONSTITUTIONAL ANEMIAS Thalassemia Sickle Cell Anemia Pyruvate Kinase Deficiency Hereditary Spherocytosis Hereditary Elliptocytosis, Including Hereditary Pyropoikilocytosis Diamond-Blackfan Anemia Fanconi Anemia Congenital Dyserythropoietic Anemia Congenital Sideroblastic Anemia Congenital Megaloblastic Anemia Part III: Erythrocytosis SECTION 1: CONSTITUTIONAL Congenital Erythrocytosis SECTION 2: ACQUIRED Acquired Erythrocytosis Part IV: Benign Leukocyte Disorders in Blood and Bone Marrow Overview of Benign Leukocyte Disorders in Blood and Bone Marrow Pancytopenia Neutropenia Neutrophilia Monocytosis Eosinophilia Basophilia Lymphocytosis Lymphopenia, Constitutional and Acquired Plasmacytosis of Bone Marrow Hematogones in Bone Marrow Lymphoid Aggregates in Bone Marrow Granulomas in Bone Marrow Part V: Constitutional Granulocytic Disorders SECTION 1: CONSTITUTIONAL NEUTROPENIAS Severe Congenital Neutropenia and Cyclic Neutropenia Shwachman-Diamond Syndrome Chediak-Higashi Syndrome Myelokathexis in WHIM Syndrome SECTION 2: CONSTITUTIONAL NEUTROPHIL ANOMALIES Pelger-Huet Anomaly MYH9-Related Disorders Selected Lysosomal Storage Diseases With Abnormal Leukocyte Granulation Part VI: Megakaryocytic Disorders Overview of Megakaryocytic Disorders SECTION 1: ACQUIRED PLATELET DISORDERS WITH THROMBOCYTOPENIA Immune-Mediated Thrombocytopenia Hemolytic-Uremic Syndrome Thrombotic Thrombocytopenic Purpura Pregnancy-Associated Thrombocytopenia SECTION 2: CONSTITUTIONAL PLATELET DISORDERS WITH THROMBOCYTOPENIA Thrombocytopenia Absent Radius Syndrome Congenital Amegakaryocytic Thrombocytopenia Gray Platelet Syndrome Wiskott-Aldrich Syndrome-Related Disorders Congenital Thrombotic Thrombocytopenic Purpura SECTION 3: THROMBOCYTOSIS Thrombocytosis Part VII: Infection Overview of Infection Hantavirus Pulmonary Syndrome Human Immunodeficiency Virus Infectious Mononucleosis Syndromes (Epstein-Barr Virus, Cytomegalovirus) Parvovirus B19 Infection Bacterial Infections, Blood and Bone Marrow Features Fungal Infections, Blood and Bone Marrow Features Helminthic Infections Malaria Other Protozoan Infections Part VIII: Miscellaneous Nonneoplastic Disorders and Conditions Overview and Classification of Hemophagocytic Disorders in Bone Marrow Hematologic Manifestations of Collagen Vascular Disorders Hematologic Manifestations of Chronic Renal Disorders Lysosomal Storage Diseases With Predominantly Histiocytic Storage Other Pregnancy-Associated Hematologic Disorders Gelatinous Transformation and Other Bone Marrow Stromal Disorders Crystals in Bone Marrow Bone Abnormalities in Bone Marrow Specimens Part IX: Myeloid Neoplasms Overview and Classification of Myeloid Neoplasms Protocol for the Examination of Specimens From Patients With Hematopoietic Neoplasms Involving Bone Marrow Clinical Practice Guidelines for Initial Work-Up of Acute Leukemia SECTION 1: MYELOPROLIFERATIVE NEOPLASMS Overview of Myeloproliferative Neoplasms Chronic Myelogenous Leukem Skryť popis