SYNTHETIC METHODS OF SINGLE-CHAIN POLYMER NANOPARTICLES Introduction Single-Chain Rings Covalent Single-Chain Polymer Nanoparticles Supramolecular Single-Chain Polymer Nanoparticles Dynamic Covalent Single-Chain Polymer Nanoparticles Conclusions and Future Outlook MOLECULAR DYNAMICS SIMULATIONS OF SINGLE-CHAIN POLYMER NANOPARTICLES Introduction Sparse Single-Chain Polymer Nanoparticles Globular Single-Chain Polymer Nanoparticles Concentrated Solutions of Single-Chain Polymer Nanoparticles Conclusions and Future Outlook CHARACTERIZATION OF SINGLE-CHAIN POLYMER NANOPARTICLES: ANALYTICAL TECHNIQUES Introduction Molar Mass Characterization Size Characterization Structural Characterization Thermal Characterization Rheological Characterization Other Techniques CHARACTERIZATION OF SINGLE-CHAIN POLYMER NANOPARTICLES: SCATTERING TECHNIQUES Introduction Small-Angle Neutron Scattering Characterization Small-Angle X-ray Scattering Characterization Static Light Scattering Characterization Dynamic Light Scattering Characterization Final Remarks DYNAMICALLY FOLDED SINGLE-CHAIN POLYMER NANOPARTICLES Introduction Single-Chain Polymer Nanoparticles vs Conventional Nanoparticles Preparation of Dynamically Folded Single-Chain Polymer Nanoparticles Characterization of Dynamically Folded Single-Chain Polymer Nanoparticles Conclusions and Outlook METALLO-CONTAINING SINGLE-CHAIN POLYMER NANOPARTICLES Introduction Single-Chain Polymer Nanoparticles vs Dendrimers Synthesis of Metallo-Containing Single-Chain Polymer Nanoparticles Characterization of Metallo-Containing Single-Chain Polymer Nanoparticles Conclusions and Future Directions COLLOIDAL UNIMOLECULAR NANOPARTICLES Introduction Synthesis of Colloidal Unimolecular Nanoparticles Characterization of Colloidal Unimolecular Nanoparticles Physico-Chemical and Rheological Properties of Colloidal Unimolecular Nanoparticles Conclusions and Future Outlook SINGLE-CHAIN NANOPARTICLES VIA SELF-FOLDING AMPHIPHILIC COPOLYMERS IN WATER Introduction Synthesis of Single-Chain Nanoparticles via Self-Folding Amphiphilic Copolymers in Water Characterization of Single-Chain Nanoparticles via Self-Folding Amphiphilic Copolymers in Water Conclusions and Future Directions APPLICATIONS OF SINGLE-CHAIN POLYMER NANOPARTICLES Introduction Protein Mimicry Nanomedicine Applications Catalysis Applications Other Uses Future Outlook