Part 1: Introducing clinical biochemistry 1 The clinical biochemistry laboratory 2 The use of the laboratory 3 Interpretation of results: general 4 Interpretation of results: diagnosis 5 Interpretation of results: monitoring 6 Analytical aspects Part 2: Core biochemistry 7 Fluid and electrolytes: basic concepts 8 Water and sodium balance: physiological mechanisms 9 Hyponatraemia: pathophysiology 10 Hyponatraemia: assessment and management 11 Hypernatraemia 12 Hyperkalaemia 13 Hypokalaemia 14 Intravenous fluid therapy 15 Investigation of renal function (1) 16 Investigation of renal function (2) 17 Urinalysis 18 Proteinuria 19 Acute kidney injury 20 Chronic kidney disease 21 Acid-base: concepts and vocabulary 22 Metabolic acid-base disorders 23 Respiratory and mixed acid-base disorders 24 Acid-base disorders: diagnosis and management 25 Proteins and enzymes 26 Immunoglobulins 27 Myocardial infarction 28 Liver function tests 29 Jaundice 30 Liver disease 31 Glucose metabolism and diabetes mellitus 32 Diagnosis and monitoring of diabetes mellitus 33 Diabetic ketoacidosis 34 Hypoglycaemia 35 Calcium regulation and hypocalcaemia 36 Hypercalcaemia 37 Phosphate and magnesium 38 Metabolic bone disease 39 Osteoporosis and fragility fractures Part 3: Endocrinology 40 Endocrine control 41 Dynamic function tests 42 Pituitary function 43 Growth disorders and acromegaly 44 Thyroid pathophysiology 45 Hypothyroidism 46 Hyperthyroidism 47 Adrenocortical pathophysiology 48 Hypofunction of the adrenal cortex 49 Hyperfunction of the adrenal cortex 50 Gonadal function 51 Subfertility Part 4: Specialized investigations 52 Nutritional assessment 53 Nutritional support 54 Parenteral nutrition 55 The metabolic response to injury 56 Gastrointestinal disorders 57 Iron 58 Zinc and copper 59 Therapeutic drug monitoring 60 Toxicology 61 Metal poisoning 62 Alcohol 63 Ascites 64 Pleural fluid 65 Cerebrospinal fluid 66 Identification of body fluids 67 Lipoprotein metabolism 68 Clinical disorders of lipid metabolism 69 Hypertension 70 Cancer and its consequences 71 Tumour markers 72 Multiple endocrine neoplasia 73 Hyperuricaemia 74 Myopathy 75 Fetal monitoring and prenatal diagnosis 76 Pregnancy 77 Antenatal screening 78 Screening the newborn for disease 79 Paediatric biochemistry 80 Inborn errors of metabolism 81 Selected inherited disorders Case history comments Online self-assessment Index Skryť popis